Leading Innovation And Discovery To Improve The Lives Of People Affected By Asbestos-Related Disease

NCARD Publications (2015 to now)


Brims FJH, Harris EJA, Murray C, Kumarasamy C, Ho A, Adler B, Franklin P, de Klerk NH. 2023. Lung cancer screening an asbestos exposed population: Existing lung cancer risk criteria are not sufficient. Respirology. https://doi.org/10.1111/resp.14487
Walker-Bone K, Benke G, Macfarlane E, Klebe S, Takahashi K, Brims F, Sim MR, Driscoll TR. 2023. Incidence and mortality from malignant mesothelioma 1982-2020 and relationship with asbestos exposure: The Australian Mesothelioma Registry. Occupational and Environmental Medicine. 80(4):186-191. https://doi.org/10.1136/oemed-2022-108669
Orozco Morales ML, Rinaldi CA, de Jong E, Lansley SM, Lee YCG, Zemek RM, Bosco A, Lake RA, Lesterhuis WJ. 2023. Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma. PLoS One. 18(5 MAY):Article e0274364. https://doi.org/10.1371/journal.pone.0274364
Katz SI, Straus CM, Roshkovan L, Blyth KG, Frauenfelder T, Gill RR, Lalezari F, Erasmus J, Nowak AK, Gerbaudo VH, et al. 2023. Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International Mesothelioma Interest Group. Journal of Thoracic Oncology. 18(3):278-298. https://doi.org/10.1016/j.jtho.2022.11.018


Ge T, Phung AL, Jhala G, Trivedi P, Principe N, De George DJ, Pappas EG, Litwak S, Sanz-Villanueva L, Catterall T, et al. 2022. Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor. Clinical and Translational Immunology. 11(11):Article e1425. https://doi.org/10.1002/cti2.1425
Forde PM, Nowak AK, Kok P-S, Brown C, Sun Z, Anagnostou V, O’Byrne KJ, Yip S, Cook A, Lesterhuis WJ, et al. 2022. DREAM3R: Durvalumab with chemotherapy as first-line treatment in advanced pleural mesothelioma-A phase 3 randomized trial. Journal of Clinical Oncology. 40(16).
Forde P, Kindler H, Zauderer M, Sun Z, Ramalingam S, Anagnostou V, Brahmer JR, Nowak AK, Kok PS, Brown C, et al. 2022. DREAM3R: DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma: A Phase 3 Randomised Trial. International Journal of Radiation Oncology Biology Physics. 112(2):E9-E10.
Rovers S, Merlin C, Fisher S, Nowak A, Pauwels P, Lardon F, Van Meerbeeck J, Smits E, Marcq E. 2022. Preclinical Investigation of Immune Checkpoint Blockade and Anti-Angiogenic Therapy in Malignant Pleural Mesothelioma. Journal of Thoracic Oncology. 17(9):S325-S325.
Zalcman G, Oulkhouir Y, Cornelissen R, Greillier L, Cid JRR, Mazieres J, Briggs P, Nowak AK, Tsao A, Fujimoto N, et al. 2022. First-line nivolumab (NIVO) plus ipilimumab (IPI) vs chemotherapy (chemo) in patients (pts) with unresectable malignant pleural mesothelioma (uMPM): 4-year update from CheckMate 743. Annals of Oncology. 33(7):S1438-S1439. https://doi.org/10.1016/j.annonc.2022.08.077
Ye L, Dick I, Chiang P, Firth T, Creaney J, Robinson BW, Redwood A. 2022. Prognostic significance of pleural effusion exhausted CD8+T cell subsets in non-small cell lung cancer and mesothelioma. Journal of Clinical Oncology. 40(16).
Keam S. 2022. Modulating the tumour microenvironment using low dose radiotherapy to improve immunotherapy efficacy in mesothelioma. https://doi.org/10.26182/fg1d-4y90
Orozco Morales L. 2022. Identifying novel therapeutic targets in mesothelioma. [PhD thesis]
Kumarasamy C, Bennett K, Franklin P, Brims F. 2022. Changing Patterns of Lung Cancer Histology in an Asbestos Exposed Population. Journal of Thoracic Oncology. 17(9):S36-S36.
Chimed-Ochir O, Rath EM, Kubo T, Yumiya Y, Lin RT, Furuya S, Brislane K, Klebe S, Nowak AK, Kang SK, et al. 2022. Must countries shoulder the burden of mesothelioma to ban asbestos? A global assessment. BMJ Global Health. 7(12):Article e010553. https://doi.org/10.1136/bmjgh-2022-010553
Brims F, Harris EJ, Kumarasamy C, Ringuet A, Adler B, Franklin P, de Klerk N, Musk B, Murray C. 2022. Correlation of lung function with ultra-low-dose CT-detected lung parenchymal abnormalities: a cohort study of 1344 asbestos exposed individuals. BMJ Open Respiratory Research. 9(1):1-6. https://doi.org/10.1136/bmjresp-2022-001366
Dang Khoa N, Phuong NL, Takahashi K, Ito K. 2022. Transport and deposition of inhaled man-made vitreous and asbestos fibers in realistic human respiratory tract models: An in silico study. Japan Architectural Review. 5(4):592-608. https://doi.org/10.1002/2475-8876.12277
Tilsed C, Principe N, Kidman J, Chin M, Orozco Morales L, Zemek R, Chee J, Islam R, Fear V, Forbes C, et al. 2022. CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy. Cell Reports. 41(13). https://doi.org/10.1016/j.celrep.2022.111874
Lau EPM, Sidhu C, Popowicz ND, Lee YCG. 2022. Pharmacokinetics of antibiotics for pleural infection. Expert Review of Respiratory Medicine. 16(10):1057-1066. https://doi.org/10.1080/17476348.2022.2147508
Jayawardena T, Vekaria S, Krivinskas S, Sidhu C, Chakera A, Lee YCG. 2022. Antibiotic administration via indwelling peritoneal catheter to treat infected malignant ascites. Respirology Case Reports. 10(11):Article e01055. https://doi.org/10.1002/rcr2.1055
Chang F, Keam S, Hoang TS, Creaney J, Gill S, Nowak AK, Ebert M, Cook AM. 2022. Immune marker expression of irradiated mesothelioma cell lines. Frontiers in Oncology. 12:Article 1020493. https://doi.org/10.3389/fonc.2022.1020493
Jeffers D, Liao YC, Takahashi K, Lin RT. 2022. Asbestos awareness among the residents of St. Kitts and Nevis: a cross-sectional study. Globalization and Health. 18(1):Article 83. https://doi.org/10.1186/s12992-022-00874-w
Zomerdijk N, Panozzo S, Mileshkin L, Yoong J, Nowak AK, Stockler MR, Philip J. 2022. Palliative care facilitates the preparedness of caregivers for thoracic cancer patients. European Journal of Cancer Care. https://doi.org/10.1111/ecc.13716
Tilsed CM, Fisher SA, Nowak AK, Lake RA, Lesterhuis WJ. 2022. Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action. Frontiers in Oncology. 12:Article 960317. https://doi.org/10.3389/fonc.2022.960317
Zemek R, Chin M, Fear V, Wylie B, Casey T, Forbes C, Tilsed C, Boon L, Guo B, Bosco A, et al. 2022. Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice. Nature Communications. 13:Article 4895. https://doi.org/10.1038/s41467-022-32567-8
Ramarao-Milne P, Kondrashova O, Patch AM, Nones K, Koufariotis LT, Newell F, Addala V, Lakis V, Holmes O, Leonard C, et al. 2022. Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels. ESMO Open. 7(4):Article 100540. https://doi.org/10.1016/j.esmoop.2022.100540
BAP1 Study Group. 2022. Response to “Revisiting ‘BAP1ness’ in Malignant Pleural Mesothelioma”. Journal of Thoracic Oncology. 17(8):e69-e70. https://doi.org/10.1016/j.jtho.2022.05.013
Carbone M, Pass HI, Ak G, Alexander HR, Baas P, Baumann F, Blakely AM, Bueno R, Bzura A, Cardillo G, …, Robinson B, et al. 2022. Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations. Journal of Thoracic Oncology. 17(7):873-889. https://doi.org/10.1016/j.jtho.2022.03.014
Boulter J, Orozco Morales ML, Principe N, Tilsed CM. 2022. What is Kindness in Science and why does it matter?. Immunology and Cell Biology. https://doi.org/10.1111/imcb.12580
Principe N, Aston WJ, Hope DE, Tilsed CM, Fisher SA, Boon L, Dick IM, Chin WL, McDonnell AM, Nowak AK, Lake RA, Chee J, Lesterhuis WJ. 2022. Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations. Frontiers in Immunology. 13:Article 872295. https://doi.org/10.3389/fimmu.2022.872295
Keam S, MacKinnon KM, Alonzo RAD, Gill S, Ebert MA, Nowak AK, Cook AM. 2022. Effects of photon radiation on DNA damage, cell proliferation, cell survival and apoptosis of murine and human mesothelioma cell lines. Advances in Radiation Oncology. Article 101013. https://doi.org/10.1016/j.adro.2022.101013
Rath EM, Takahashi K, Yuen ML, Odgerel CO, Lin RT, Soeberg M, Nowak AK. 2022. The Ecological Association between Asbestos Consumption and Asbestos-Related Diseases 15 Years Later. Environmental Health Perspectives. 130(5):Article 057703. https://doi.org/10.1289/EHP11148
Creaney J, Patch AM, Addala V, Sneddon SA, Nones K, Dick IM, Lee YCG, Newell F, Rouse EJ, Naeini MM, Kondrashova O, Lakis V, Nakas A, Waller D, Sharkey A, Mukhopadhyay P, Kazakoff SH, Koufariotis LT, Davidson AL, Ramarao-Milne P, Holmes O, Xu Q, Leonard C, Wood S, Grimmond SM, Bueno R, Fennell DA, Pearson JV, Robinson BW, Waddell N. 2022. Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma. Genome Medicine. 14(1):Article 58. https://doi.org/10.1186/s13073-022-01060-8
Martens M, Kreidl F, Ehrhart F, Jean D, Mei M, Mortensen HM, Nash A, Nymark P, Evelo CT, Cerciello F. 2022. A Community-Driven, Openly Accessible Molecular Pathway Integrating Knowledge on Malignant Pleural Mesothelioma. Frontiers in Oncology. 12:Article 849640. https://doi.org/10.3389/fonc.2022.849640
Gill S, Nowak AK, Bowyer S, Endersby R, Ebert MA, Cook A. 2022. Clinical evidence for synergy between immunotherapy and radiotherapy ( SITAR ). Journal of Medical Imaging and Radiation Oncology. https://doi.org/10.1111/1754-9485.13441
Kindler HL, Novello S, Bearz A, Ceresoli GL, Aerts JGJV, Spicer J, Taylor P, Nackaerts K, Greystoke A, Jennens R, Calabrò L, Burgers JA, Santoro A, Cedrés S, Serwatowski P, Ponce S, Van Meerbeeck JP, Nowak AK, Blumenschein G, Siegel JM, Kasten L, Köchert K, Walter AO, Childs BH, Elbi C, Hassan R, Fennell DA. 2022. Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial. The Lancet Oncology. 23(4):540-552. https://doi.org/10.1016/S1470-2045(22)00061-4
Newton JC, O’Connor M, Saunders C, Ali S, Nowak AK, Halkett GKB. 2022. “Who can I ring? Where can I go?” Living with advanced cancer whilst navigating the health system: a qualitative study. Supportive Care in Cancer. https://doi.org/10.1007/s00520-022-07107-1
Dick IM, Lee YCG, Cheah HM, Miranda A, Robinson BWS, Creaney J. 2022. Profile of soluble factors in pleural effusions predict prognosis in mesothelioma. Cancer Biomarkers. 33(1):159-169. https://doi.org/10.3233/CBM-210280
Louw A, Panou V, Szejniuk WM, Meristoudis C, Chai SM, van Vliet C, Lee YCG, Dick IM, Firth T, Lynggaard LA, Asghari AB, Vyberg M, Hansen J, Creaney J, Røe OD. 2022. BAP1 Loss by Immunohistochemistry Predicts Improved Survival to First-Line Platinum and Pemetrexed Chemotherapy for Patients With Pleural Mesothelioma: A Validation Study. Journal of Thoracic Oncology. 17(7):921-930. https://doi.org/10.1016/j.jtho.2022.04.008
Redwood AJ, Dick IM, Creaney J, Robinson BWS. 2022. What’s next in cancer immunotherapy? – The promise and challenges of neoantigen vaccination. OncoImmunology. 11(1):Article 2038403. https://doi.org/10.1080/2162402X.2022.2038403
Fitzgerald DB, Sidhu C, Budgeon C, Tan AL, Read CA, Kwan BCH, Smith NA, Fysh ET, Muruganandan S, Saghaie T, Shrestha R, Badiei A, Nguyen P, Burke A, Goddard J, Windsor M, McDonald J, Wright G, Czarnecka K, Sivakumar P, Yasufuku K, Feller-Kopman DJ, Maskell NA, Murray K, Lee YCG. 2022. Australasian Malignant PLeural Effusion (AMPLE)-3 trial: study protocol for a multi-centre randomised study comparing indwelling pleural catheter (±talc pleurodesis) versus video-assisted thoracoscopic surgery for management of malignant pleural effusion. Trials. 23(1):Article 530. https://doi.org/10.1186/s13063-022-06405-7
Jhala G, Krishnamurthy B, Brodnicki TC, Ge T, Akazawa S, Selck C, Trivedi PM, Pappas EG, Mackin L, Principe N, Brémaud E, De George DJ, Boon L, Smyth I, Chee J, Kay TWH, Thomas HE. 2022. Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse. Cell Reports. 39(4):110747. https://doi.org/10.1016/j.celrep.2022.110747
Peters S, Scherpereel A, Cornelissen R, Oulkhouir Y, Greillier L, Kaplan MA, Talbot T, Monnet I, Hiret S, Baas P, Nowak AK, Fujimoto N, Tsao AS, Mansfield AS, Popat S, Zhang X, Hu N, Balli D, Spires T, Zalcman G. 2022. First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743. Annals of Oncology. 33(5):488-499. https://doi.org/10.1016/j.annonc.2022.01.074
Tilsed CM, Casey TH, de Jong E, Bosco A, Zemek RM, Salmons J, Wan G, Millward MJ, Nowak AK, Lake RA, Lesterhuis WJ. 2022. Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy. Frontiers in Oncology. 12:Article 849793. https://doi.org/10.3389/fonc.2022.849793
Louw A, van Vliet C, Peverall J, Colkers S, Acott N, Creaney J, Lee YCG, Chai SM. 2022. Analysis of early pleural fluid samples in patients with mesothelioma: A case series exploration of morphology, BAP1, and CDKN2A status with implications for the concept of mesothelioma in situ in cytology. Cancer Cytopathology. 130(5):352-362. https://doi.org/10.1002/cncy.22548
Robinson BWS, Redwood AJ, Creaney J. 2022. How Our Continuing Studies of the Pre-clinical Inbred Mouse Models of Mesothelioma Have Influenced the Development of New Therapies. Frontiers in Pharmacology. 13:Article 858557. https://doi.org/10.3389/fphar.2022.858557
Breen LJ, Huseini T, Same A, Peddle-McIntyre CJ, Lee YCG. 2022. Living with mesothelioma: A systematic review of patient and caregiver psychosocial support needs. Patient Education and Counseling. https://doi.org/10.1016/j.pec.2022.02.017
Scherpereel A, Antonia S, Bautista Y, Grossi F, Kowalski D, Zalcman G, Nowak AK, Fujimoto N, Peters S, Tsao AS, Mansfield AS, Popat S, Sun X, Lawrance R, Zhang X, Daumont MJ, Bennett B, McKenna M, Baas P. 2022. First-line nivolumab plus ipilimumab versus chemotherapy for the treatment of unresectable malignant pleural mesothelioma: patient-reported outcomes in CheckMate 743. Lung Cancer. 167:8-16. https://doi.org/10.1016/j.lungcan.2022.03.012
Kok PS, Forde PM, Hughes B, Sun Z, Brown C, Ramalingam S, Cook A, Lesterhuis WJ, Yip S, O’Byrne K, Pavlakis N, Brahmer J, Anagnostou V, Ford K, Fitzpatrick K, Bricker A, Cummins MM, Stockler M, Nowak AK. 2022. Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trial. BMJ Open. 12(1):Article e057663. https://doi.org/10.1136/bmjopen-2021-057663
ESMO Guidelines Committee. 2022. Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆. Annals of Oncology. 33(2):129-142. https://doi.org/10.1016/j.annonc.2021.11.005
Sooda A, Rwandamuriye F, Wanjalla CN, Jing L, Koelle DM, Peters B, Leary S, Chopra A, Calderwood MA, Mallal SA, Pavlos R, Watson M, Phillips EJ, Redwood AJ. 2022. Abacavir inhibits but does not cause self-reactivity to HLA-B*57:01-restricted EBV specific T cell receptors. Communications Biology. 5(1):Article 133. https://doi.org/10.1038/s42003-022-03058-9
Armato SG, Nowak AK, Francis RJ, Katz SI, Kholmatov M, Blyth KG, Gudmundsson E, Kidd AC, Gill RR. 2022. Imaging in pleural mesothelioma: A review of the 15th International Conference of the International Mesothelioma Interest Group. Lung Cancer. 164:76-83. https://doi.org/10.1016/j.lungcan.2021.12.008
Nowak AK, Jackson A, Sidhu C. 2022. Management of Advanced Pleural Mesothelioma-At the Crossroads. JCO oncology practice. 18(2):116-124. https://doi.org/10.1200/OP.21.00426
Jeffery E, Lee YCG, Newton RU, Lyons-Wall P, McVeigh J, Fitzgerald DB, Straker L, Peddle-McIntyre CJ. 2022. Changes in body composition in patients with malignant pleural mesothelioma and the relationship with activity levels and dietary intake. European Journal of Clinical Nutrition. https://doi.org/10.1038/s41430-021-01062-6
Lee YCG. 2022. Bedside ultrasonography to determine pleurodesis success: SIMPLE but how sound?. The Lancet Respiratory Medicine. 10(2):122-123. https://doi.org/10.1016/S2213-2600(21)00441-0
Orozco Morales ML, Rinaldi CA, de Jong E, Lansley SM, Gummer JPA, Olasz B, Nambiar S, Hope DE, Casey TH, Lee YCG, Leslie C, Nealon G, Shackleford DM, Powell AK, Grimaldi M, Balaguer P, Zemek RM, Bosco A, Piggott MJ, Vrielink A, Lake RA, Lesterhuis WJ. 2022. PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective. Iscience. 25(1):Article 103571. https://doi.org/10.1016/j.isci.2021.103571


Tilsed C. 2021. How does chemotherapy cure? Exploring and exploiting the immune system to transform the tumor microenvironment and improve chemotherapy efficacy. https://doi.org/10.26182/4b3h-3342
Nowak AK, Chin WL, Keam S, Cook A. 2021. Immune checkpoint inhibitor therapy for malignant pleural mesothelioma. Lung Cancer. 162:162-168. https://doi.org/10.1016/j.lungcan.2021.11.006
Nowak AK. 2021. CONFIRMing single-drug immune checkpoint blockade efficacy in mesothelioma. The Lancet Oncology. 22(11):1485-1487. https://doi.org/10.1016/S1470-2045(21)00516-7
Nuismer SL, Layman NC, Redwood AJ, Chan B, Bull JJ. 2021. Methods for measuring the evolutionary stability of engineered genomes to improve their longevity. Synthetic Biology. 6(1):Article ysab018. https://doi.org/10.1093/synbio/ysab018
Sidhu C, Louw A, Gary Lee YC. 2021. Malignant Pleural Mesothelioma: Updates for Respiratory Physicians. Clinics in Chest Medicine. 42(4):697-710. https://doi.org/10.1016/j.ccm.2021.08.006
Li S, Simoni Y, Zhuang S, Gabel A, Ma S, Chee J, Islas L, Cessna A, Creaney J, Bradley RK, Redwood A, Robinson BW, Newell EW. 2021. Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies. Proceedings of the National Academy of Sciences of the United States of America. 118(30):Article e2025570118. https://doi.org/10.1073/pnas.2025570118
Öjlert ÅK, Nebdal D, Snapkov I, Olsen V, Kidman J, Greiff V, Chee J, Helland Å. 2021. Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor. Molecular Oncology. https://doi.org/10.1002/1878-0261.13082
Dart SJ, Cook AM, Millward MJ, McDonnell AM, Chin WL, Hakeem MU, Meniawy TM, Bowyer SE. 2021. Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors. Scientific Reports. 11(1):Article 15312. https://doi.org/10.1038/s41598-021-93479-z
Baas P, Scherpereel A, Nowak AK, Oukessou A, Zalcman G. 2021. Heterogeneity of treatment effects in malignant pleural mesothelioma – Authors’ reply. The Lancet. 398(10297):302. https://doi.org/10.1016/S0140-6736(21)00876-X
Chan B, Arapović M, Masters LL, Rwandamuiye F, Jonjić S, Smith LM, Redwood AJ. 2021. The m15 locus of murine cytomegalovirus modulates natural killer cell responses to promote dissemination to the salivary glands and viral shedding. Pathogens. 10(7):Article 866. https://doi.org/10.3390/pathogens10070866
Behrouzfar K, Burton K, Mutsaers SE, Morahan G, Lake RA, Fisher SA. 2021. How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers. Frontiers in Oncology. 11:Article 679609. https://doi.org/10.3389/fonc.2021.679609
Francis RJ, Bailey DL, Hofman MS, Scott AM. 2021. The australasian radiopharmaceutical trials network: Clinical trials, evidence, and opportunity. Journal of Nuclear Medicine. 62(6):755-756. https://doi.org/10.2967/jnumed.120.258152
Khoor A, Bironzo P, Bueno R, Nowak A, Schmitt F. 2021. Localized mesothelioma. In Thoracic Tumours: WHO Classification of Tumours. 5th ed. World Health Organization. ISBN: 978-92-832-4506-3
Sauter JL, Bueno R, Dacic S, Gill RR, Husain AN, Kadota K, Ladanyi M, Nowak A, Schmitt F. 2021. Diffuse Pleural Mesothelioma. In Thoracic Tumours: WHO Classification of Tumours. 5th ed. World Health Organization. ISBN: 978-92-832-4506-3
Alves E, Taifour S, Dolcetti R, Chee J, Nowak AK, Gaudieri S, Blancafort P. 2021. Reprogramming the anti-tumor immune response via CRISPR genetic and epigenetic editing. Molecular Therapy – Methods and Clinical Development. 21:592-606. https://doi.org/10.1016/j.omtm.2021.04.009
Charng J, Attia MS, Arunachalam S, Lam W-S, Creaney J, Muruganandan S, Read C, Millward M, Spiro J, Chakera A, Lee YCG, Nowak AK, Chen FK. 2021. Increased interdigitation zone visibility on optical coherence tomography following systemic fibroblast growth factor receptor 1-3 tyrosine kinase inhibitor anticancer therapy. Clinical & Experimental Ophthalmology. https://doi.org/10.1111/ceo.13940
Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å. 2021. NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma. Journal of Translational Medicine. 19(1):Article 232. https://doi.org/10.1186/s12967-021-02905-3
Philip J, Le Gautier R, Collins A, Nowak AK, Le B, Crawford GB, Rankin N, Krishnasamy M, Mitchell G, McLachlan SA, IJzerman M, Hudson R, Rischin D, Sousa TV, Sundararajan V. 2021. Care plus study: a multi-site implementation of early palliative care in routine practice to improve health outcomes and reduce hospital admissions for people with advanced cancer: a study protocol. BMC Health Services Research. 21(1):Article 513. https://doi.org/10.1186/s12913-021-06476-3
Louw A, Lee YCG, Acott N, Creaney J, van Vliet C, Chai SM. 2021. Diagnostic utility of BAP1 for malignant pleural mesothelioma in pleural fluid specimens with atypical morphology. Cytopathology. https://doi.org/10.1111/cyt.13015
Creemers JHA, Lesterhuis WJ, Mehra N, Gerritsen WR, Figdor CG, de Vries IJM, Textor J. 2021. A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery. Journal for ImmunoTherapy of Cancer . 9(5):Article e002032. https://doi.org/10.1136/jitc-2020-002032
Principe N, Kidman J, Lake RA, Lesterhuis WJ, Nowak AK, McDonnell AM, Chee J. 2021. Malignant Pleural Effusions—A Window Into Local Anti-Tumor T Cell Immunity?. Frontiers in Oncology. 11:Article 672747. https://doi.org/10.3389/fonc.2021.672747
Cook AM, McDonnell A, Millward MJ, Creaney J, Hasani A, McMullen M, Meniawy T, Robinson BWS, Lake RA, Nowak AK. 2021. A phase 1b clinical trial optimizing regulatory T cell depletion in combination with platinum-based chemotherapy in thoracic cancers. Expert Review of Anticancer Therapy. https://doi.org/10.1080/14737140.2021.1882308
Fitzgerald DB, Popowicz ND, Joseph J, Butcher SC, Westcott M, Lim EM, Creaney J, Lee YCG. 2021. Trace element levels in pleural effusions. Health  Science Reports. 4(2):Article e262. https://doi.org/10.1002/hsr2.262
Popowicz N, Cheah HM, Gregory C, Miranda A, Dick IM, Lee YCG, Creaney J. 2021. Neutrophil-to-lymphocyte ratio in malignant pleural fluid: Prognostic significance. PLoS One. 16(4):Article e0250628. https://doi.org/10.1371/journal.pone.0250628
Harris EJA, Lim KP, Moodley Y, Adler B, Sodhi-Berry N, Reid A, Murray CP, Franklin PJ, Musk AW, de Klerk NH, Brims FJH. 2021. Low dose CT detected interstitial lung abnormalities in a population with low asbestos exposure. American Journal of Industrial Medicine. https://doi.org/10.1002/ajim.23251
Baas P, Scherpereel A, Nowak AK, Fujimoto N, Peters S, Tsao AS, Mansfield AS, Popat S, Jahan T, Antonia S, Oulkhouir Y, Bautista Y, Cornelissen R, Greillier L, Grossi F, Kowalski D, Rodríguez-Cid J, Aanur P, Oukessou A, Baudelet C, Zalcman G. 2021. First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial. The Lancet. 397(10272):375-386. https://doi.org/10.1016/S0140-6736(20)32714-8
Carey RN, Pfau JC, Fritzler MJ, Creaney J, de Klerk N, W (Bill) Musk A, Franklin P, Sodhi-Berry N, Brims F, Reid A. 2021. Autoantibodies and cancer among asbestos-exposed cohorts in Western Australia. Journal of Toxicology and Environmental Health – Part A: Current Issues. https://doi.org/10.1080/15287394.2021.1889424
Cheah HM, Fitzgerald D, Louw A, Creaney J, Lee YCG. 2021. Hyaluronic acid in viscous malignant mesothelioma pleural effusion. Respirology Case Reports. 9(1):Article e00694. https://doi.org/10.1002/rcr2.694
D’Alonzo RA, Gill S, Rowshanfarzad P, Keam S, MacKinnon KM, Cook AM, Ebert MA. 2021. In vivo noninvasive preclinical tumor hypoxia imaging methods: a review. International Journal of Radiation Biology. https://doi.org/10.1080/09553002.2021.1900943
Durber K, Halkett GKB, McMullen M, Nowak AK. 2021. Measuring financial toxicity in Australian cancer patients – Validation of the COmprehensive Score for financial Toxicity (FACT COST) measuring financial toxicity in Australian cancer patients. Asia-Pacific Journal of Clinical Oncology. https://doi.org/10.1111/ajco.13508
Fear V, Forbes C, Neeve S, Fisher S, Chee J, Waithman J, Ma S, Lake R, Nowak A, Creaney J, Brown M, Saunders C, Robinson B. 2021. Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used. Cancer immunology, immunotherapy. https://doi.org/10.1007/s00262-021-02934-3
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Lee YCG, Creaney J. 2021. Endomicroscopy of the pleura highlights challenges and limitations of pleuroscopy. Respirology. 26(2):138-139. https://doi.org/10.1111/resp.13982
Marcq E, Van Audenaerde JRM, De Waele J, Merlin C, Pauwels P, Van Meerbeeck JP, Fisher SA, Smits ELJ. 2021. The search for an interesting partner to combine with PD-L1 blockade in mesothelioma: Focus on TIM-3 and LAG-3. Cancers. 13(2):1-14. https://doi.org/10.3390/cancers13020282
Nowak AK. 2021. New and old treatments for malignant mesothelioma: not just immunotherapy. The Lancet Respiratory Medicine. https://doi.org/10.1016/S2213-2600(20)30516-6
Ye L, Creaney J, Redwood A, Robinson B. 2021. The Current Lung Cancer Neoantigen Landscape and Implications for Therapy. Journal of Thoracic Oncology. https://doi.org/10.1016/j.jtho.2021.01.1624
Brims F, Leong T, Stone E, Harden S, Marshall H, Navani N, Stirling R. Variations in lung cancer care and outcomes: How best to identify and improve standards of care? Respirology, 2021.26:1103-1105. https://doi.org/10.1111/resp.14155
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Brims FJH, Kong K, Harris EJA, Sodhi-Berry N, Reid A, Murray CP, Franklin PJ, Musk AB, De Klerk NH. 2020. Pleural plaques and the risk of lung cancer in asbestos-exposed subjects. American Journal of Respiratory and Critical Care Medicine. 201(1):57-62. https://doi.org/10.1164/rccm.201901-0096OC
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Cerciello F, Choi M, Sinicropi-Yao SL, Lomeo K, Amann JM, Felley-Bosco E, Stahel RA, Robinson BWS, Creaney J, Pass HI, Vitek O, Carbone DP. 2020. Verification of a blood-based targeted proteomics signature for malignant pleural mesothelioma. Cancer Epidemiology Biomarkers and Prevention. 29(10):1973-1982. https://doi.org/10.1158/1055-9965.EPI-20-0543
Chee J, Wilson C, Buzzai A, Wylie B, Forbes CA, Booth M, Principe N, Foley B, Cruickshank MN, Waithman J. 2020. Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model. Epigenetics. 15(1-2):1-11. https://doi.org/10.1080/15592294.2019.1656156
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Hoon SN, Fyfe K, Peddle-Mcintyre CJ, Bowyer S, Hawkins F, Jeffery E, Chih HJ, Creaney J, Nowak A, Brims F. 2020. Randomised placebo-controlled cross-over study examining the role of anamorelin in mesothelioma (The ANTHEM study): Rationale and protocol. BMJ Open Respiratory Research. 7(1):Article e000551. https://doi.org/10.1136/bmjresp-2019-000551
Jia Q, Chiu L, Wu S, Bai J, Peng L, Zheng L, Zang R, Li X, Yuan B, Gao Y, Wu D, Li X, Wu L, Sun J, He J, Robinson BWS, Zhu B. 2020. Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non-Small Cell Lung Cancer. Advanced Science. 7(9):Article 1903410. https://doi.org/10.1002/advs.201903410
Keam S, Gill S, Ebert MA, Nowak AK, Cook AM. 2020. Enhancing the efficacy of immunotherapy using radiotherapy. Clinical and Translational Immunology. 9(9):Article e1169. https://doi.org/10.1002/cti2.1169
Kidman J, Principe N, Watson M, Lassmann T, Holt RA, Nowak AK, Lesterhuis WJ, Lake RA, Chee J. 2020. Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses. Frontiers in Immunology. 11:Article 587014. https://doi.org/10.3389/fimmu.2020.587014
Lam WS, Creaney J, Chen FK, Chin WL, Muruganandan S, Arunachalam S, Attia MS, Read C, Murray K, Millward M, Spiro J, Chakera A, Gary Lee YC, Nowak AK. 2020. A phase II trial of single oral FGF inhibitor, AZD4547, as second or third line therapy in malignant pleural mesothelioma. Lung Cancer. 140:87-92. https://doi.org/10.1016/j.lungcan.2019.12.018
Louw A, Creaney J, Thomas A, Van Vliet C, Harvey NT, Wood BA, Mesbah Ardakani N. 2020. Histologically Diverse BAP1-Deficient Melanocytic Tumors in a Patient With BAP1 Tumor Predisposition Syndrome. The American Journal of Dermatopathology. 42(11):872-875. https://doi.org/10.1097/DAD.0000000000001719
Louw A, Sidhu C, Fitzgerald D, Creaney J, Chai SM, Lee YCG. 2020. Clump material within drainage chest tubes contain diagnostic information: A proof-of-concept case series. The European Respiratory Journal. 57(3). https://doi.org/10.1183/13993003.03248-2020
Louw A, Wallace C, Chai SM, Amanuel B, Wong DD. 2020. ALK positive malignant peritoneal mesothelioma mimicking inflammatory myofibroblastic tumour: a diagnostic pitfall. Pathology. 52(6):719-722. https://doi.org/10.1016/j.pathol.2020.06.016
MacMillan M, Roy B, McLaren S, Nowak AK, Thomas R, Lee YCG. 2020. Widespread pulmonary invasion by malignant pleural mesothelioma: an important diagnostic consideration. Respirology Case Reports. 8(9):Article e00675. https://doi.org/10.1002/rcr2.675
Mo L, Adler B, Green C, Brims FJH. 2020. Malignant mesothelioma presenting as a solitary perifissural nodule. Internal Medicine Journal. 50(12):1592-1594. https://doi.org/10.1111/imj.15120
Newton JC, O’Connor M, Saunders C, Moorin R, Ali S, Nowak AK, Halkett GKB. 2020. The role of psychosocial support in the experiences of people living with advanced cancer: A qualitative exploration of patients’ perspectives. Psycho-Oncology. https://doi.org/10.1002/pon.5569
Nicholson AG, Sauter JL, Nowak AK, Kindler HL, Gill RR, Remy-Jardin M, Armato SG, Fernandez-Cuesta L, Bueno R, Alcala N, Foll M, Pass H, Attanoos R, Baas P, Beasley MB, Brcic L, Butnor KJ, Chirieac LR, Churg A, Courtiol P, Dacic S, De Perrot M, Frauenfelder T, Gibbs A, Hirsch FR, Hiroshima K, Husain A, Klebe S, Lantuejoul S, Moreira A, Opitz I, Perol M, Roden A, Roggli V, Scherpereel A, Tirode F, Tazelaar H, Travis WD, Tsao MS, van Schil P, Vignaud JM, Weynand B, Lang-Lazdunski L, Cree I, Rusch VW, Girard N, Galateau-Salle F. 2020. EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach. Journal of Thoracic Oncology. 15(1):29-49. https://doi.org/10.1016/j.jtho.2019.08.2506
Nowak AK, Brosseau S, Cook A, Zalcman G. 2020. Antiangiogeneic Strategies in Mesothelioma. Frontiers in Oncology. 10:Article 126. https://doi.org/10.3389/fonc.2020.00126
Nowak AK, Lesterhuis WJ, Kok PS, Brown C, Hughes BGM, Karikios DJ, John T, Kao SCH, Leslie C, Cook AM, Pavlakis N, Briscoe K, O’Byrne KJ, Karapetis CS, Lam WS, Langford A, Yip S, Stockler MR. 2020. Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in. The Lancet Oncology. 21(9):1213-1223. https://doi.org/10.1016/S1470-2045(20)30462-9
Principe N, Kidman J, Goh S, Tilsed CM, Fisher SA, Fear VS, Forbes CA, Zemek RM, Chopra A, Watson M, Dick IM, Boon L, Holt RA, Lake RA, Nowak AK, Lesterhuis WJ, McDonnell AM, Chee J. 2020. Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy. Frontiers in Immunology. 11:Article 584423. https://doi.org/10.3389/fimmu.2020.584423
Roshkovan L, Thompson JC, Katz SI, Deshpande C, Jenkins T, Nowak AK, Francis R, Dennie C, Fabre D, Singhal S, Galperin-Aizenberg M. 2020. Alveolar adenoma of the lung: Multidisciplinary case discussion and review of the literature. Journal of Thoracic Disease. 12(11):6847-6853. https://doi.org/10.21037/jtd-20-1831
Scherpereel A, Antonia S, Bautista Y, Grossi F, Kowalski D, Zalcman G, Nowak A, Fujimoto N, Peters S, Tsao A, Mansfield A, Popat S, Sun X, Padilla B, Aanur P, Daumont M, Bennett B, McKenna M, Baas P. 2020. First-line nivolumab (NIVO) plus ipilimumab (IPI) versus chemotherapy (chemo) for the treatment of unresectable malignant pleural mesothelioma (MPM): Patient-reported outcomes (PROs) from CheckMate 743. Annals of Oncology. 31:S1441-S1441. https://doi.org/10.1016/j.annonc.2020.10.603
Tsao AS, Baas P, Nowak A, Zalcman G, Fujimoto N, Peters S, Baudelet C, Aanur P, Osawa M, Tendolkar A, Feng Y, Sheng J. 2020. Evaluation of flat dosing for nivolumab (NIVO) plus ipilimumab (IPI) in first-line (1L) unresectable malignant pleural mesothelioma (MPM): CheckMate 743 (CM 743). Annals of Oncology. 31:S1445-S1445. https://doi.org/10.1016/j.annonc.2020.10.556
Ye L, Mesbah Ardakani N, Thomas C, Spilsbury K, Leslie C, Amanuel B, Millward M. 2020. Detection of Low-level EGFR c.2369 C > T (p.Thr790Met) Resistance Mutation in Pre-treatment Non-small Cell Lung Carcinomas Harboring Activating EGFR Mutations and Correlation with Clinical Outcomes. Pathology and Oncology Research. https://doi.org/10.1007/s12253-020-00833-z
Zemek RM, Chin WL, Nowak AK, Millward MJ, Lake RA, Lesterhuis WJ. 2020. Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy. Frontiers in Immunology. 11:Article 223. https://doi.org/10.3389/fimmu.2020.00223
Zemek RM, Fear VS, Forbes C, de Jong E, Casey TH, Boon L, Lassmann T, Bosco A, Millward MJ, Nowak AK, Lake RA, Lesterhuis WJ. 2020. Bilateral murine tumor models for characterizing the response to immune checkpoint blockade. Nature Protocols. https://doi.org/10.1038/s41596-020-0299-3


Nowak A, Armato SG. 2019. Measuring Malignant Pleural Mesothelioma. Ceresoli GL, Bombardieri E, D’Incalci M, editors. In Mesothelioma: From Research to Clinical Practice. NY: Springer. pp. 153-166. https://doi.org/10.1007/978-3-030-16884-1_10
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Aston WJ, Hope DE, Cook AM, Boon L, Dick I, Nowak AK, Lake RA, Lesterhuis WJ. 2019. Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment. OncoImmunology. https://doi.org/10.1080/2162402X.2019.1641390
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Chin WL, Zemek RM, Lesterhuis WJ, Lassmann T. 2019. Functional genomics in cancer immunotherapy: Computational approaches for biomarker and drug discovery. Molecular Systems Design and Engineering. 4(4):689-700. https://doi.org/10.1039/c9me00029a
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Fear VS, Forbes CA, Chee J, Ma S, Neeve S, Celliers L, Fisher SA, Dick I, Creaney J, Robinson BWS. 2019. Neo-antigen specific T cell responses indicate the presence of metastases before imaging. Scientific Reports. 9(1). https://doi.org/10.1038/s41598-019-51317-3
Fennell DA, Baas P, Taylor P, Nowak AK, Gilligan D, Nakano T, Pachter JA, Weaver DT, Scherpereel A, Pavlakis N, van Meerbeeck JP, Cedres S, Nolan L, Kindler H, Aerts JGJV. 2019. Maintenance Defactinib Versus Placebo After First-Line Chemotherapy in Patients With Merlin-Stratified Pleural Mesothelioma: COMMAND-A Double-Blind, Randomized, Phase II Study. Journal of Clinical Oncology. 37(10):790-798. https://doi.org/10.1200/JCO.2018.79.0543
Fennell DA, Taylor P, Gilligan D, Nakano T, Scherpereel A, Pavlakis N, Van Meerbeeck JP, Aerts JGJV, Nowak AK, Kindler H, Baas P. 2019. Reply to K. Masuda et al. Journal of Clinical Oncology. 37(25):2294-2295. https://doi.org/10.1200/JCO.19.01208
Ferjancic P, Ebert MA, Nowak AK, Francis RJ, Jeraj R. 2019. Test-Retest Repeatability of 18F-FET PET in Small Volumes. Medical Physics. 46(6):E398-E398.
Gill RR, Tsao AS, Kindler HL, Richards WG, Armato SG, Francis RJ, Gomez DR, Dahlberg S, Rimner A, Simone CB, de Perrot M, Blumenthal G, Adjei AA, Bueno R, Harpole DH, Hesdorffer M, Hirsch FR, Pass HI, Yorke E, Rosenzweig K, Burt B, Fennell DA, Lindwasser W, Malik S, Peikert T, Mansfield AS, Salgia R, Yang H, Rusch VW, Nowak AK. 2019. Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee – International Association for the Study of Lung Cancer – Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting. Journal of Thoracic Oncology. 14(10):1718-1731. https://doi.org/10.1016/j.jtho.2019.08.012
Harris E, Franklin P, Sodhi-Berry N, Olsen N, Musk A, Reid A, De Klerk N, Brims F. 2019. Metformin may reduce mesothelioma and lung cancer incidence among asbestos-exposed. Respirology. 24:163-163.
Harris EJA, Kao S, McCaughan B, Nakano T, Kondo N, Hyland R, Nowak AK, de Klerk NH, Brims FJH. 2019. Prediction modelling using routine clinical parameters to stratify survival in Malignant Pleural Mesothelioma patients undergoing cytoreductive surgery. Journal of Thoracic Oncology. 14(2):288-293. https://doi.org/10.1016/j.jtho.2018.10.005
Harris EJA, Musk AW, DeKlerk N, Brims FJH. 2019. Comment on: “Low-dose computed tomography screening for lung cancer in people with workplace exposure to asbestos”. Lung Cancer. 136:148-149. https://doi.org/10.1016/j.lungcan.2019.04.019
Jeffery E, Lee YCG, Newton RU, Lyons-Wall P, McVeigh J, Nowak AK, Cheah HM, Nguyen B, Fitzgerald DB, Creaney J, Straker L, Peddle-McIntyre CJ. 2019. Body composition and nutritional status in malignant pleural mesothelioma: implications for activity levels and quality of life. European Journal of Clinical Nutrition. 73(10):1412-1421. https://doi.org/10.1038/s41430-019-0418-9
Kamiya H, Peters S, Sodhi-Berry N, Reid A, Gordon L, de Klerk N, Brims F, Musk AW, Franklin P. 2019. Validation of an Asbestos Job-Exposure Matrix (AsbJEM) in Australia: Exposure-Response Relationships for Malignant Mesothelioma. Annals of Work Exposures and Health. 63(7):719-728. https://doi.org/10.1093/annweh/wxz038
Lam W, Nowak A, Chen F, Muruganandan S, Arunachalam S, Chin M, Millward M, Read C, Murray K, Creaney J, Lee YCG. 2019. Phase II Trial of an Oral FGFR Inhibitor AZD4547 as Second or Third Line Therapy in Malignant Pleural Mesothelioma: Final Results of FRAME Study. Journal of Thoracic Oncology. 14(10):S342-S342. https://doi.org/10.1016/j.jtho.2019.08.691
Lépine PA, Thomas R, Nguyen S, Lacasse Y, Cheah HM, Creaney J, Muruganandan S, Martel S, Lee YCG, Delage A. 2019. Simplified criteria using pleural fluid cholesterol and lactate dehydrogenase to distinguish between exudative and transudative pleural effusions. Respiration. 98(1):48-54. https://doi.org/10.1159/000496396
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Ma S, Chee J, Fear VS, Forbes CA, Boon L, Dick IM, Robinson BWS, Creaney J. 2019. Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome. OncoImmunology. Article 1684714. https://doi.org/10.1080/2162402X.2019.1684714
Mendoza TR, Williams LA, Keating KN, Siegel J, Elbi C, Nowak AK, Hassan R, Cuffel B, Cleeland CS. 2019. Evaluation of the psychometric properties and minimally important difference of the MD Anderson Symptom Inventory for malignant pleural mesothelioma (MDASI-MPM). Journal of Patient-Reported Outcomes. 3(1):Article 34. https://doi.org/10.1186/s41687-019-0122-5
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Nowak AK, Forde PM. 2019. Immunotherapy trials in mesothelioma — promising results, but don’t stop here. Nature Reviews Clinical Oncology. 16:726-728. https://doi.org/10.1038/s41571-019-0291-4
Nowak AK, McDonnell A, Cook A. 2019. Immune checkpoint inhibition for the treatment of mesothelioma. Expert Opinion on Biological Therapy. 19(7). https://doi.org/10.1080/14712598.2019.1606209
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Tsao A, Nakano T, Nowak AK, Popat S, Scagliotti GV, Heymach J. 2019. Targeting angiogenesis for patients with unresectable malignant pleural mesothelioma. Seminars in Oncology. 46(2):145-154. https://doi.org/10.1053/j.seminoncol.2019.06.001
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Wylie B, Chee J, Forbes CA, Booth M, Stone SR, Buzzai A, Abad A, Foley B, Cruickshank MN, Waithman J. 2019. Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens. OncoImmunology. https://doi.org/10.1080/2162402X.2019.1609874
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Humphries T, Robinson C, Giardina T, Nowak A, Robinson S, Iacopetta B, Stewart C, Meniawy T, Kumarasinghe P, Wood B, Thomas C, De Boer B, Leung Y, Robbins P, Van Hazel G, Ferguson T, Raftopoulos S, Millward M, Amanuel B. 2018. Clinical implementation of personalised medicine for six high priority WA cancers. Asia-Pacific Journal of Clinical Oncology. 14:157-158.
Kamiya H, De Klerk N, Peters S, Sodhi-Berry N, Olsen N, Brims F, Musk AWB, Franklin P. 2018. Validation of an asbestos job-exposure matrix: Exposure-response relationships for malignant mesothelioma. Respirology. 23:202-202. https://doi.org/10.1093/annweh/wxz038
Lansley S, Della Vergiliana JV, Creaney J, Lee Y. 2018. Bacteria as Novel Anti-Mesothelioma Agents. Journal of Thoracic Oncology. 13(10):S750-S750. https://doi.org/10.1016/j.jtho.2018.08.1275
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Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors and Pathology Committees. 2018. Eighth edition staging of thoracic malignancies: Implications for the reporting pathologist. Archives of Pathology and Laboratory Medicine. 142(5):645-661. https://doi.org/10.5858/arpa.2017-0245-RA
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Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R. 2018. Scientific Advances and New Frontiers in Mesothelioma Therapeutics. Journal of Thoracic Oncology. 13(9):1269-1283. https://doi.org/10.1016/j.jtho.2018.06.011
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Patch AM, Nones K, Kazakoff SH, Newell F, Wood S, Leonard C, Holmes O, Xu Q, Addala V, Creaney J, Robinson BW, Fu S, Geng C, Li T, Zhang W, Liang X, Rao J, Wang J, Tian M, Zhao Y, Teng F, Gou H, Yang B, Jiang H, Mu F, Pearson JV, Waddell N. 2018. Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing. PLoS One. 13(1):Article e0190264. https://doi.org/10.1371/journal.pone.0190264
Popowicz ND, Fitzgerald D, Joseph J, Lim EM, Cheah HM, Butcher S, Creaney J, Lee YCG. 2018. Trace element concentrations in human pleural effusions. Abstract from The Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Adelaide, Australia.
Popowicz ND, Gregory CL, Miranda AK, Cheah HM, Dick IM, Lee YCG, Creaney J. 2018. Prognostic significance of the neutrophil to lymphocyte ratio in pleural fluid.
Reid A, Franklin P, Berry G, Peters S, Sodhi-Berry N, Brims F, Musk AW, De Klerk NH. 2018. Are children more vulnerable to mesothelioma than adults? A comparison of mesothelioma risk among children and adults exposed non-occupationally to blue asbestos at Wittenoom. Occupational and Environmental Medicine. 75(12):898-903. https://doi.org/10.1136/oemed-2018-105108
Reid A, Franklin P, de Klerk N, Creaney J, Brims F, Musk B, Pfau J. 2018. Autoimmune antibodies and asbestos exposure: Evidence from Wittenoom, Western Australia. American Journal of Industrial Medicine. 61(7):615-620. https://doi.org/10.1002/ajim.22863
Sneddon SA, Dick IM, Lee YC, Musk AW, Allcock RJ, Waddell N, Patch A-M, Pearson JV, Holt RA, Robinson BW, Creaney J. 2018. Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations. Lung Cancer. 119:64-70. https://doi.org/10.1016/j.lungcan.2018.03.009
TCGA Research Network. 2018. Integrative molecular characterization of malignant pleural mesothelioma. Cancer Discovery. 8(12):1549-1565. https://doi.org/10.1158/2159-8290.CD-18-0804
The Cancer Genome Atlas Network. 2018. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 173(2):291-304.e6. https://doi.org/10.1016/j.cell.2018.03.022
The Cancer Genome Atlas Network. 2018. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems. 6(3):282-300.e2. https://doi.org/10.1016/j.cels.2018.03.003
The Cancer Genome Atlas Research Network, Creaney J. 2018. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 173(2):305-320.e10. https://doi.org/10.1016/j.cell.2018.03.033
The Cancer Genome Atlas Research Network. 2018. A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell. 33(4):690-705.e9. https://doi.org/10.1016/j.ccell.2018.03.014
The Cancer Genome Atlas Research Network. 2018. A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell. 173(2):386-399.e12. https://doi.org/10.1016/j.cell.2018.03.027
The Cancer Genome Atlas Research Network. 2018. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. Cell Systems. 7(4):422-437.e7. https://doi.org/10.1016/j.cels.2018.08.010
The Cancer Genome Atlas Research Network. 2018. An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell. 173(2):400-416.e11. https://doi.org/10.1016/j.cell.2018.02.052
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The Cancer Genome Atlas Research Network. 2018. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. Cell Reports. 25(5):1304-1317.e5. https://doi.org/10.1016/j.celrep.2018.10.001
The Cancer Genome Atlas Research Network. 2018. Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell. 33(4):676-689.e3. https://doi.org/10.1016/j.ccell.2018.03.007
The Cancer Genome Atlas Research Network. 2018. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports. 23(1):239-254.e6. https://doi.org/10.1016/j.celrep.2018.03.076
The Cancer Genome Atlas Research Network. 2018. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports. 23(1):194-212.e6. https://doi.org/10.1016/j.celrep.2018.03.063
The Cancer Genome Atlas Research Network. 2018. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell. 33(4):706-720.e9. https://doi.org/10.1016/j.ccell.2018.03.006
The Cancer Genome Atlas Research Network. 2018. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports. 23(1):172-180.e3. https://doi.org/10.1016/j.celrep.2018.03.046
The Cancer Genome Atlas Research Network. 2018. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 173(2):338-354.e15. https://doi.org/10.1016/j.cell.2018.03.034
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The Cancer Genome Atlas Research Network. 2018. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 173(2):355-370.e14. https://doi.org/10.1016/j.cell.2018.03.039
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The Cancer Genome Atlas Research Network. 2018. The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports. 23(1):313-326.e5. https://doi.org/10.1016/j.celrep.2018.03.075
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Musk ABW, de Klerk N, Brims FJ. 2017. Mesothelioma in australia: A review. Medical Journal of Australia. 207(10):449-452. https://doi.org/10.5694/mja17.00397
Novello S, Nowak AK, Grosso F, Steele N, Popat S, Greillier L, John T, Leighl NB, Reck M, Pavlakis N, Sorensen JB, Planchard D, Ceresoli GL, Hughes B, Mazieres J, Socinski MA, von Wangenheim U, Barrueco J, Morsli N, Scagliotti G. 2017. Overall survival (OS) and forced vital capacity (FVC) results from the LUME-Meso study of nintedanib (N) plus pemetrexed/cisplatin (PEM/CIS) vs placebo (P) plus PEM/CIS in chemo-naive patients (pts) with malignant pleural mesothelioma (MPM). Annals of Oncology. 28.
Scagliotti GV, Gaafar R, Nowak AK, Reck M, Tsao AS, van Meerbeeck J, Vogelzang NJ, Nakano T, von Wangenheim U, Velema D, Morsli N, Popat S. 2017. LUME-Meso: Design and Rationale of the Phase III Part of a Placebo-Controlled Study of Nintedanib and Pemetrexed/Cisplatin Followed by Maintenance Nintedanib in Patients With Unresectable Malignant Pleural Mesothelioma. Clinical Lung Cancer. 18(5):589-593. https://doi.org/10.1016/j.cllc.2017.03.010
Sneddon S, Patch AM, Dick IM, Kazakoff SH, Pearson JV, Waddell N, Allcock RJN, Holt RA, Robinson BWS, Creaney J. 2017. Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma. BMC Cancer. 17(1):Article 396. https://doi.org/10.1186/s12885-017-3382-6
Sodhi-Berry N, De Klerk N, Franklin P, Brims F, Peters S, Olsen N, Musk A. 2017. 0402 Does lung cancer incidence and mortality differ with the type of asbestos fibre? : evidence from Western Australia. Occupational and Environmental Medicine. 74(S1):A126. https://doi.org/10.1136/oemed-2017-104636.330
Weber M, Yap S, Goldsbury D, Manners D, Tammemagi M, Marshall H, Brims F, McWilliams A, Fong K, Kang YJ, Caruana M, Banks E, Canfell K. 2017. Identifying high risk individuals for targeted lung cancer screening: Independent validation of the PLCOm2012 risk prediction tool. International Journal of Cancer. 141(2):242-253. https://doi.org/10.1002/ijc.30673



Lam W-S, Nowak A. 2016. Chemotherapy in Malignant Pleural Mesothelioma. Mineo TC, editor. In Malignant Pleural Mesothelioma: Present Status and Future Directions. Bentham Science Publishers. pp. 305-320. https://doi.org/10.2174/9781681081946116010025
ASLC Staging and Prognostic Factors Committee, Advisory Boards, and Participating Institutions. 2016. The IASLC lung cancer staging project: Methodology and validation used in the development of proposals for revision of the stage classification of NSCLC in the Forthcoming (Eighth) Edition of the TNM Classification of Lung Cancer. Journal of Thoracic Oncology. 11(9):1433-1446. https://doi.org/10.1016/j.jtho.2016.06.028
Armato SG, Blyth KG, Keating JJ, Katz S, Tsim S, Coolen J, Gudmundsson E, Opitz I, Nowak AK. 2016. Imaging in pleural mesothelioma: A review of the 13th International Conference of the International Mesothelioma Interest Group. Lung Cancer. 101:48-58. https://doi.org/10.1016/j.lungcan.2016.09.003
Azzopardi M, Lee YC. 2016. Pleural Effusion Management in Malignant Pleural Mesothelioma. Mineo TC, editor. In Malignant Pleural Mesothelioma: Present Status and Future Directions. 1st ed. USA: Betham. pp. 285-303. https://doi.org/10.2174/97816810819461160101
Azzopardi M, Thomas R, Muruganandan S, Lam DCL, Garske LA, Kwan BCH, Rashid Ali MRS, Nguyen PT, Yap E, Horwood FC, Ritchie AJ, Bint M, Tobin CL, Shrestha R, Piccolo F, De Chaneet CC, Creaney J, Newton RU, Hendrie D, Murray K, Read CA, Feller-Kopman D, Maskell NA, Lee YCG. 2016. Protocol of the Australasian Malignant Pleural Effusion-2 (AMPLE-2) trial: A multicentre randomised study of aggressive versus symptom-guided drainage via indwelling pleural catheters. BMJ Open. 6(7):Article e011480. https://doi.org/10.1136/bmjopen-2016-011480
Bintcliffe OJ, Lee GYC, Rahman NM, Maskell NA. 2016. The management of benign non-infective pleural effusions. European Respiratory Review. 25(141):303-316. https://doi.org/10.1183/16000617.0026-2016
Brims F, Meniawy T, Duffus I, De Fonseka D, Segal A, Creaney J, Maskell N, Lake R, De Klerk N, Nowak A. 2016. A novel clinical prediction model for prognosis in malignant pleural mesothelioma using decision tree analysis. Journal of Thoracic Oncology. 11(4):573-582. https://doi.org/10.1016/j.jtho.2015.12.108
Brims FJ, McWilliams A, Fong K. 2016. Lung cancer screening in Australia: Progress or procrastination?: There is progress internationally with lung cancer screening but far slower headway in Australia. Medical Journal of Australia. 204(1):4-4.e1. https://doi.org/10.5694/mja15.01109
Cook A, McDonnell A, Lake R, Nowak A. 2016. Dexamethasone co-medication in cancer patients undergoing chemotherapy causes substantial immunomodulatory effects with implications for chemo-immunotherapy strategies. OncoImmunology. 5(3):Article e1066062. https://doi.org/10.1080/2162402X.2015.1066062
Cook AM, Lesterhuis WJ, Nowak AK, Lake RA. 2016. Chemotherapy and immunotherapy: Mapping the road ahead. Current Opinion in Immunology. 39:23-29. https://doi.org/10.1016/j.coi.2015.12.003
Cornwall SMJ, Wikstrom M, Musk AW, Alvarez J, Nowak AK, Nelson DJ. 2016. Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes. OncoImmunology. 5(2). https://doi.org/10.1080/2162402X.2015.1082028
Creaney J, Dick I, Musk AW, Olsen NJ, Robinson BWS. 2016. Immune response profiling of malignant pleural mesothelioma for diagnostic and prognostic biomarkers. Biomarkers. 21(6):551-561. https://doi.org/10.3109/1354750X.2016.1160429
Creaney J, Lee GCG. 2016. Diagnoses (not diagnosis) of pleural effusion: Time to consider concurrent etiologies. Annals of the American Thoracic Society. 13(7):1003-1004. https://doi.org/10.1513/AnnalsATS.201604-320ED
Francis RJ, Nowak AK. 2016. Radiology: Nuclear Imaging. Light RW, Lee YCG, editors. In Textbook of Pleural Diseases (3rd Edition). 3rd ed. CRC Press. pp. 234-243.
Franklin P, Alfonso H, Reid A, Olsen N, Shilkin K, Brims F, de Klerk N, Musk AW. 2016. Asbestos exposure and histological subtype of malignant mesothelioma. Occupational and Environmental Medicine. 73(11):749-752. https://doi.org/10.1136/oemed-2016-103721
Franklin P, Reid A, Olsen N, Peters S, De Klerk N, Brims F, Threlfall T, Murray R, Musk A. 2016. Incidence of malignant mesothelioma in Aboriginal people in Western Australia. Australian and New Zealand Journal of Public Health. 40(4):383-387. https://doi.org/10.1111/1753-6405.12542
Goldstraw P, Chansky K, Crowley J, Rami-Porta R, Asamura H, Eberhardt WEE, Nicholson AG, Groome P, Mitchell A, Bolejack V, Ball D, Beer DG, Beyruti R, Detterbeck F, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Huang J, Kennedy C, Kim J, Kim YT, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom EM, Van Meerbeeck J, Nakano T, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier JP, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas CF, Travis W, Tsao MS, Turrisi A, Vansteenkiste J, Watanabe H, Wu YL, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso PL, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Abad Cavaco F, Ansótegui Barrera E, Abal Arca J, Parente Lamelas I, Arnau Obrer A, Guijarro Jorge R, Bascom GK, Blanco Orozco AI, González Castro M, Blum MG, Chimondeguy D, Cvijanovic V, Defranchi S, De Olaiz Navarro B, Escobar Campuzano I, Macía Vidueira I, Fernández Araujo E, Andreo García F, Fong KM, Francisco Corral G, Cerezo González S, Freixinet Gilart J, García Arangüena L, García Barajas S, Girard P, Goksel T. 2016. The IASLC lung cancer staging project: Proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM Classification for lung cancer. Journal of Thoracic Oncology. 11(1):39-51. https://doi.org/10.1016/j.jtho.2015.09.009
Greening DW, Ji H, Chen M, Robinson BWS, Dick IM, Creaney J, Simpson RJ. 2016. Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo. Scientific Reports. 6:Article 32643 . https://doi.org/10.1038/srep32643
Kondola S, Manners D, Nowak A. 2016. Malignant pleural mesothelioma: an update on diagnosis and treatment options. THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE. 10(3):275-288. https://doi.org/10.1177/1753465816628800
Lansley SM, Pedersen B, Robinson C, Searles RG, Sterrett G, Van Bruggen I, Lake RA, Mutsaers SE, Prele C. 2016. A subset of malignant mesothelioma tumors retain osteogenic potential. Scientific Reports. 6:Article 36349. https://doi.org/10.1038/srep36349
McDonnell AM. 2016. T cell phenotype and receptor expression in pleural effusions associated with malignant mesothelioma: Abstracts of ICI 2016 International Congress of Immunology, 21-26 August 2016, Melbourne, Australia. European Journal Immunology. 46(S1). https://doi.org/10.1002/eji.201670200
Meniawy T, Lake R, Mcdonnell A, Millward M, Nowak A. 2016. PD-L1 on peripheral blood T lymphocytes is prognostic in patients with non-small cell lung cancer (NSCLC) treated with EGFR inhibitors. Lung Cancer. 93:9-16. https://doi.org/10.1016/j.lungcan.2015.12.006
Morré DJ, Hostetler B, Taggart DJ, Morré DM, Musk AW, Robinson BWS, Creaney J. 2016. ENOX2-based early detection (ONCOblot) of asbestos-induced malignant mesothelioma 4-10 years in advance of clinical symptoms. Clinical Proteomics. 13(1). https://doi.org/10.1186/s12014-016-9103-3
Murray CP, Wong PM, Teh J, De Klerk N, Rosenow T, Alfonso H, Reid A, Franklin P, Musk A, Brims F. 2016. Ultra low dose CT screen-detected non-malignant incidental findings in the Western Australian Asbestos Review Programme. Respirology. 21(8):1419-1424. https://doi.org/10.1111/resp.12826
Musk A, Gordon L, Alfonso H, Reid A, Olsen N, Mina R, Franklin P, Brims F, Hui J, De Klerk N. 2016. MALIGNANT MESOTHELIOMA IN SUBJECTS WITH NO KNOWN EXPOSURE TO ASBESTOS: A CASE-CONTROL STUDY. Respirology. 21:178-178.
Musk AWBWB, Nowak AK, De Klerk NH. 2016. Asbestos exposure: Challenges for Australian clinicians. Medical Journal of Australia. 204(2):48-48.e1. https://doi.org/10.5694/mja15.01072
Nowak A, Chansky K, Rice DC, Pass HI, Kindler HL, Shemanski L, Billé A, Rintoul RC, Batirel HF, Thomas CF, Friedberg J, Cedres S, De Perrot M, Rusch VW. 2016. The IASLC Mesothelioma Staging Project: proposals for revisions of the T descriptors in the forthcoming eighth edition of the TNM classification for pleural mesothelioma. Journal of Thoracic Oncology. 11(12):2089-2099. https://doi.org/10.1016/j.jtho.2016.08.147
Pass H, Giroux D, Kennedy C, Ruffini E, Cangir AK, Rice D, Asamura H, Waller D, Edwards J, Weder W, Hoffmann H, Van Meerbeeck JP, Nowak A, Rusch VW. 2016. The IASLC Mesothelioma Staging Project: Improving Staging of a Rare Disease Through International Participation. Journal of Thoracic Oncology. 11(12):2082-2088. https://doi.org/10.1016/j.jtho.2016.09.123
Popowicz ND, Gregory CL, Cheah HM, Lee YC, Creaney J. 2016. Prognostic Significance Of Neutrophil To Lymphocyte Ratio In Pleural Fluid And Blood Of Patients With Malignant Mesothelioma: ATS 2016, Vol 193. Abstract from American Thoracic Society International Conference, .
Psallidas I, Kalomenidis I, Porcel JM, Robinson B, Stathopoulos GT. 2016. Malignant pleural effusion: From bench to bedside. European Respiratory Review. 25(140):189-198. https://doi.org/10.1183/16000617.0019-2016
Rice D, Chansky K, Nowak A, Pass H, Kindler H, Shemanski L, Opitz I, Call S, Hasegawa S, Kernstine K, Atinkaya C, Rea F, Nafteux P, Rusch VW. 2016. The IASLC Mesothelioma Staging Project: Proposals for Revisions of the N Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Pleural Mesothelioma. Journal of Thoracic Oncology. 11(12):2100-2111. https://doi.org/10.1016/j.jtho.2016.09.121
Robles AI, Olsen KS, Tsui DWT, Georgoulias V, Creaney J, Dobra K, Vyberg M, Minato N, Anders RA, Børresen-Dale AL, Zhou J, Sætrom P, Nielsen BS, Kirschner MB, Krokan HE, Papadimitrakopoulou V, Tsamardinos I, Røe OD. 2016. Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: Innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine. 14(1):Article 295. https://doi.org/10.1186/s12967-016-1059-6
Rusch VW, Chansky K, Kindler HL, Nowak A, Pass HI, Rice DC, Shemanski L, Galateau-Sallé F, Mccaughan BC, Nakano T, Ruffini E, Van Meerbeeck JP, Yoshimura M. 2016. The IASLC Mesothelioma Staging Project: Proposals for the M Descriptors and for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Mesothelioma. Journal of Thoracic Oncology. 11(12):2112-2119. https://doi.org/10.1016/j.jtho.2016.09.124
Stathopoulos GT, Lee YC, Robinson BW. 2016. Experimental Models: Pleural Diseases. Light RW, Lee YCG, editors. In Textbook of Pleural Diseases. 3rd ed. Taylor & Francis. pp. 125-144.
Steven A, Fisher SA, Robinson BW. 2016. Immunotherapy for lung cancer. Respirology. 21(5):821-833. https://doi.org/10.1111/resp.12789
Thomas R, Cheah H, Creaney J, Turlach B, Lee G. 2016. Longitudinal Measurement of Pleural Fluid Biochemistry and Cytokines in Malignant Pleural Effusions. Chest. 149(6):1494-1500. https://doi.org/10.1016/j.chest.2016.01.001
Travis WD, Asamura H, Bankier AA, Beasley MB, Detterbeck F, Flieder DB, Goo JM, MacMahon H, Naidich D, Nicholson AG, Powell CA, Prokop M, Rami-Porta R, Rusch V, Van Schil P, Yatabe Y, Goldstraw P, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Eberhardt WEE, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim YT, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom EM, Van Meerbeeck J, Mitchell A, Nakano T, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Saijo N, Sculier JP, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas CF, Tsao MS, Turrisi A, Vansteenkiste J, Watanabe H, Wu YL, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso PL, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E. 2016. The IASLC lung cancer staging project: Proposals for coding T categories for subsolid nodules and assessment of tumor size in part-solid tumors in the forthcoming eighth edition of the TNM classification of lung cancer. Journal of Thoracic Oncology. 11(8):1204-1223. https://doi.org/10.1016/j.jtho.2016.03.025



Armato III SG, Coolen J, Nowak A, Robinson C, Gill RR, Straus C, Khanwalkar A. 2015. Imaging in pleural mesothelioma: A review of the 12th International Mesothelioma Interest Group. Lung Cancer. 90(2):148-154. https://doi.org/10.1016/j.lungcan.2015.07.011
Birnie KA, Yip YY, Ng DCH, Kirschner MB, Reid G, Prêle C, Musk A, Lee G, Thompson P, Mutsaers S, Badrian B. 2015. Loss of miR-223 and JNK signaling contribute to elevated stathmin in malignant pleural mesothelioma. Molecular Cancer Research. 13(7):1106-1118. https://doi.org/10.1158/1541-7786.MCR-14-0442
Cook A, Khong A, Nowak AK, Lake RA. 2015. Novel insights into the pathophysiology and treatment of malignant pleural mesothelioma. Lung Cancer Management. 4(5):249-259. https://doi.org/10.2217/lmt.15.23
Creaney J, Dick IM, Robinson BW. 2015. Comparison of mesothelin and fibulin-3 in pleural fluid and serum as markers in malignant mesothelioma. Current Opinion in Pulmonary Medicine. 21(4):352-356. https://doi.org/10.1097/MCP.0000000000000167
Creaney J, Ma S, Sneddon SA, Tourigny M, Dick I, Leon J, Khong A, Fisher S, Lake R, Lesterhuis W, Nowak A, Leary S, Watson MW, Robinson B. 2015. Strong spontaneous tumor neoantigen responses induced by a natural human carcinogen. OncoImmunology. 4(7):1-7. https://doi.org/10.1080/2162402X.2015.1011492
Creaney J, Robinson BWS. 2015. Author’s response: Inconsistent results or inconsistent methods? A plea for standardisation of biomarker sampling in mesothelioma studies. Thorax. 70(4):374-375. https://doi.org/10.1136/thoraxjnl-2014-206564
Francis R, Segard T, Morandeau L, Lee G, Millward M, Segal A, Nowak A. 2015. Characterization of hypoxia in malignant pleural mesothelioma with FMISO PET-CT. Lung Cancer. 90(1):55-60. https://doi.org/10.1016/j.lungcan.2015.07.015
Hjerpe A, Ascoli V, Bedrossian C, Boon M, Creaney J, Davidson B, Dejmek A, Dobra K, Fassina A, Field A, Firat P, Kamei T, Kobayashi T, Michael C, Onder S, Segal A, Vielh P. 2015. Guidelines for cytopathologic diagnosis of epithelioid and mixed type malignant mesothelioma. Complementary statement from the International Mesothelioma Interest Group, also endorsed by the International Academy of Cytology and the Papanicolaou Society of Cytopathology. CytoJournal. 12(26):Article 170726. https://doi.org/10.4103/1742-6413.170726
Hjerpe A, Ascoli V, Bedrossian CWM, Boon ME, Creaney J, Davidson B, Dejmek A, Dobra K, Fassina A, Field A, Firat P, Kamei T, Kobayashi T, Michael CW, Önder S, Segal A, Vie P. 2015. Guidelines for the Cytopathologic Diagnosis of Epithelioid and Mixed-Type Malignant Mesothelioma: a secondary publication. Cytopathology. 26(3):142-156. https://doi.org/10.1111/cyt.12250
Hjerpe A, Ascoli V, Bedrossian CWM, Boon ME, Creaney J, Davidson B, Dejmek A, Dobra K, Fassina A, Field A, Firat P, Kamei T, Kobayashi T, Michael CW, Önder S, Segal A, Vielh P. 2015. Guidelines for the cytopathologic diagnosis of epithelioid and mixed-type malignant mesothelioma: Complementary Statement from the International Mesothelioma Interest Group, Also Endorsed by the International Academy of Cytology and the Papanicolaou Society of Cytopathology. Diagnostic Cytopathology. 43(7):563-576. https://doi.org/10.1002/dc.23271
Johnson C, Saunders C, Phillips M, Emery J, Nowak A, Overheu K, Ward AM, Joske DJL. 2015. Randomized Controlled Trial of Shared Care for Patients With Cancer Involving General Practitioners and Cancer Specialists. Journal of Oncology Practice. 11(5):349-355. https://doi.org/10.1200/JOP.2014.001569
Leong SL, Lee G, Robinson B, Creaney J. 2015. Role of Mesothelin Measurement in Patients With Cytology-Negative Pleural Effusion Undergoing Medical Thoracoscopy. PLEURA. N/A:1-7. https://doi.org/10.1177/2373997515579639
Leong SL, Zainudin R, Kazan-Allen L, Robinson B. 2015. Asbestos in Asia. Respirology. 20(4):548-555. https://doi.org/10.1111/resp.12517
Lesterhuis W, Rinaldi C, Jones A, Rozali E, Dick I, Khong A, Boon L, Robinson B, Nowak A, Bosco A, Lake R. 2015. Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations. Scientific Reports. 5:1-11. https://doi.org/10.1038/srep12298
Lim CB, Prêle C, Baltic S, Arthur P, Creaney J, Neil Watkins D, Thompson P, Mutsaers S. 2015. Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis. Oncotarget. 6(3):1519-1530. https://doi.org/10.18632/oncotarget.2729
Mccoy M, Hemmings C, Miller T, Austin SJ, Bulsara MK, Zeps N, Nowak A, Lake R, Platell C. 2015. Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer. British Journal of Cancer. 113(12):1677-1686. https://doi.org/10.1038/bjc.2015.427
Mcdonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie A, Robinson B. 2015. Restoration of defective cross-presentation in tumors by gemcitabine. OncoImmunology. 4(5):e1005501. https://doi.org/10.1080/2162402X.2015.1005501
Mcdonnell A, Lesterhuis W, Khong A, Nowak A, Lake R, Currie AJ, Robinson B. 2015. Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy. European Journal of Immunology. 45(1):49-59. https://doi.org/10.1002/eji.201444722
Meniawy T, Lake R, McDonnell A, Millward M, Nowak A. 2015. Up regulation of PD-L1 on peripheral blood CD3+T cells predicts poor prognosis in patients with non-small cell lung cancer (NSCLC) treated with epidermal growth factor receptor (EGFR) inhibitors. European Journal of Cancer. 51(S3):S47-S47. https://doi.org/10.1016/S0959-8049(16)30148-4, https://doi.org/10.1016/S0959-8049(16)30148-4
Nowak A, Cook A, Mcdonnell A, Millward M, Creaney J, Francis R, Hasani A, Segal A, Musk A, Turlach B, Mccoy M, Robinson B, Lake R. 2015. A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma. Annals of Oncology. 26(12):2483-2490. https://doi.org/10.1093/annonc/mdv387
Nowak AK, Lesterhuis-Vasbinder D, Lesterhuis WJ. 2015. New directions in mesothelioma treatment. Lung Cancer Management. 4(6):299-307. https://doi.org/10.2217/lmt.15.32
Robinson C, Dick I, Wise M, Holloway A, Diyagama D, Robinson B, Creaney J, Lake R. 2015. Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma. BMC Cancer. 15:Article 983. https://doi.org/10.1186/s12885-015-1953-y
Sneddon S, Leon J, Dick I, Cadby G, Olsen N, Brims F, Allcock R, Moses E, Melton P, De Klerk N, Musk A, Robinson B, Creaney J. 2015. Absence of germline mutations in BAP1 in sporadic cases of malignant mesothelioma. Gene. 563(1):103-105. https://doi.org/10.1016/j.gene.2015.03.031