Dr Nandini Makwana

DR NANDINI MAKWANA

RESEARCH FELLOW

Nandini completed her bachelor’s in microbiology and master’s in health science from the University of Pune, India. She began her career as a research assistant at the National Institute of Virology, India, which is recognised as a WHO Collaborating Center for arboviruses and hemorrhagic fever reference and research. She moved on to work at the National AIDS Research Institute for a couple of years, where she conducted research on anti-retroviral drugs. Nandini received her PhD degree in 2017 from the University of Western Australia; her research was to understand the effects of cytomegalovirus on immune cells in kidney transplant patients. She later worked as a research scientist on cancer immunotherapy for a private company, Selvax Pty Ltd. She joined NCARD in February 2019. Her research interest lies in identifying tumour neo-antigens and using them as personalised cancer vaccines.

CURRENT PROJECTS

  • Improving Mesothelioma Therapy by Boosting Immune Responses to Mutations by Vaccination and by Immunogenic Chemotherapy.  Funding body: USA, Department of Defense (DoD) PI: Prof. Bruce Robinson. Co-PIs Prof. Jenette Creaney and Associate Prof. Alec Redwood

RECENT HIGHLIGHTS / PUBLICATIONS

  • Lee, Silvia., Doualeh, Mariam., Affandi, Jacquita S., Makwana, Nandini., Irish, Ashley., Price, Patricia (2019). Functional and clinical consequences of changes to natural killer cell phenotypes driven by chronic cytomegalovirus infections. Journal of Medical Virology, 91(6):1120-1127. PMID: 30636352
  • Ariyanto, Ibnu A., Estiasari, Riwanti., Edwar, Lukman., Makwana, Nandini., Lee, Silvia., Price, Patricia (2019). Characterisation of natural killer cells in HIV patients beginning therapy with a high burden of Cytomegalovirus. Immunological Investigations, DOI:10.1080/08820139.2018.1538236. PMID: 30422022
  • Makwana, Nandini., Waters, Shelley., Irish, Ashley., Howson, Prue., Price, Patricia (2019). Deciphering Effects of Uncontrolled Cytomegalovirus Replication on Immune Responses in Cytomegalovirus DNA-Positive Renal Transplant Recipients. Viral Immunology, 32 (8): 355-360. PMID: 31536468
  • Makwana, Nandini., Foley, Bree., Fernandez, Sonia., Lee, Silvia., Irish, Ashley., Pircher, Hanspeter., Price, Patricia (2017) CMV drives the expansion of highly functional memory T cells expressing NK cell receptors in renal transplant recipients. European Journal of Immunology, 1324–1334. PMID: 28586095
  • Suryawanshi, Rahul., Jadhav, Sushama., Makwana, Nandini., Desai, Dipen., Chaturbhuj, Devidas., Sonawani, Archana., Idicula-Thomas, Susan., Murugesan, Vanangamudi., Katti, Seturam B., Tripathy, Srikanth (2017). Evaluation of 4-thiazolidinone derivatives as potential reverse transcriptase inhibitors against HIV-1 drug resistant strains. Bioorganic & Medicinal Chemistry, 211–218. PMID: 28236450
  • Makwana, Nandini B., Foley, Bree., Lee, Silvia., Fernandez, Sonia., Irish, Ashley B., Price, Patricia (2016). Asymptomatic CMV infections in long-term renal transplant recipients are associated with the loss of FcRγ from LIR-1+ NK cells. European Journal of Immunology, 2597–2608. PMID: 27562679

MORE INFORMATION

Menu